139437-48-2

Upstream product

• 98-03-3 thiophene-2-carbaldehyde 
• 56613-80-0 D-2-phenylglycinol 

Downstream Products

• 154777-14-7 (4R-1'R)-4-(2'-hydroxy-1'-phenylethylamino)-4-(2-thienyl)-butanal dimethyl acetal 
• 139437-60-8 (1'R,2R)-2-amino>-2-phenylethanol 
• 139437-60-8 (1'S,2R)-2-phenyl-2-amino>ethanol 
• 139437-64-2 (R)-2-[Methyl-((R)-1-thiophen-2-yl-ethyl)-amino]-2-phenyl-ethanol 
• 139437-68-6 (R)-2-[Methyl-((S)-1-thiophen-2-yl-ethyl)-amino]-2-phenyl-ethanol 
• 1011296-20-0 (R)-2-phenyl-2-[(R)-1-(2-thienyl)but-3-enylamino]ethanol 
• 1011296-34-6 (R)-2-phenyl-[(1R,2R)-1-(2-thienyl)-2-phenylbut-3-enylamino]ethanol 
• 154777-17-0 (2R,5S,8R)-2-phenyl-8-(2-thienyl)-1-aza-4-oxabicyclo<3.3.0>octane 

Relevant academic research and scientific papers

Diastereoselective addition of silyl enol ether to chiral imines and 1,3-oxazolidines using a Lewis acid

The Lewis acid promoted reaction of silyl enol ether to chiral imines and 1,3-oxazolidines derived from (R)-phenylglycinol afforded with good diastereoselectivity the (R,R)-β-amino ester derivatives from the imines, and the (R,S)-β-amino ester derivatives from the 1,3-oxazolidines.

Asymmetric Synthesis of (1R,1'R)- and (1S,1'S)-Bis(1-arylethyl)amines by way of a Diastereoselective Addition to Chiral Imines and Oxaxolidines with Organometallic Reagents

The asymmetric synthesis of the bis(α-methylbenzyl)amines, (1R,1'R)- and (1S,1'S)-bis(1-arylethyl)amines 6, utilizing a diastereoselective reaction of chiral imines and oxazolidines derived from (R)-phenylglycinol with organometallic reagents, is describe

Diastereoselective addition of chiral imines and 1,3-oxazolidines with Grignard reagents; asymmetric synthesis of (R)-2-aryl- and (R,R)-2,5-bis(aryl)pyrrolidines

Asymmetric syntheses of (R)-2-aryl- and (R,R)-2,5-bis(aryl)pyrrolidines were described starting from chiral aromatic imines derived from (R)-phenylglycinol, in which the diastereoselective additions of Grignard reagents to the chiral imines and 1,3-oxazol

DIASTEREOSELECTIVE ADDITION OF ORGANOMETALLIC REAGENTS TO CHIRAL IMINES AND 1,3-OXAZOLIDINES

The reaction of MeLi or MeMgBr with chiral aromatic imines and 2-aryl-1,3-oxazolidines derived from (R)-phenylglycinol afforded with good diastereoselectivity (R,R)-amines from imines, but the (R,S)-amines from 1,3-oxazolidines, respectively.