139446-54-1Relevant academic research and scientific papers
Rh-catalyzed highly enantioselective synthesis of 3-arylbutanoic acids
Sun, Xianfeng,Zhou, Le,Wang, Chun-Jiang,Zhang, Xumu
, p. 2623 - 2626 (2008/02/13)
(Chemical Equation Presented) It's in the mix: The reaction conditions - catalyst, additive, and solvent - have been optimized for the asymmetric hydrogenation of 3-aryl-3-butenoic acids. The rigid, chiral bisphospholane ligand (SP,RC)-DuanPhos is crucial to achieving high enantioselectivity.
3-Aryl-3-butenoic Acids and Their Esters: Practical Synthesis from Diketene by the Palladium-Catalyzed Grignard Coupling Reaction and Application as Monomers for the Radical Copolymerization with Styrene
Itoh, Kenji,Harada, Tatsumi,Nagashima, Hideo
, p. 3746 - 3748 (2007/10/02)
Treatment of arylmagnesium bromide with an equimolar amount of zinc chloride followed by the reaction with diketene in the presence of a catalytic amount of PdCl2(PPh3)2 provided an improved synthetic method for 3-aryl-3-butenoic acid in a large scale.App
