139460-10-9Relevant articles and documents
Facile methods for preparation of thiazolopyridine and tetrahydrothiazolopyridine derivatives
Haginoya, Noriyasu,Komoriya, Satoshi,Osanai, Ken,Yoshino, Toshiharu,Nagata, Tsutomu,Nagamochi, Masatoshi,Muto, Ryo,Yamaguchi, Mitsuhiro,Nagahara, Takayasu,Kanno, Hideyuki
, p. 1555 - 1561 (2004)
The improved routes to prepare tetrahydrothiazolo[5,4-c]-pyridine-2- carboxylic acid lithium salts (2 and 3) were developed. Route A is consisted of the improved preparation of thiazolopyridine intermediates, and Route B is applicable for a large scale synthesis of tetrahydrothiazolo[5,4-c]pyridine-2- carboxylic acid derivatives. The methods we developed may serve as facile means for preparing thiazolopyridine and tetrahydrothiazolopyridine derivatives.
COMPOUNDS FOR TREATMENT OF DRUG RESISTANT AND PERSISTENT TUBERCULOSIS
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Paragraph 00271, (2014/12/12)
Described herein are compounds and compositions for treating drug resistant and persistent tuberculosis. Also described herein is a method of screening for identifiying biofilm formation inhibitors.
β-lactam compounds and process for producing the same
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, (2008/06/13)
Novel β-lactam compound of the formula [1]: wherein R1is lower alkyl or hydroxy-substituted lower alkyl, R2is H or lower alkyl, X is O or, S, R3is H, metal or protecting group, W is a 6- or 7-membered nitrogen-containing heterocycle optionally being substituted at carbon atoms. Said β-lactam compound shows excellent antibacterial activity against Gram-positive bacteria, particularly against methicillin-resistantStaphylococcus aureusand methicillin-resistant and coagulase-negativeStaphylococcus aureus.