139461-67-9

Basic information

• Product Name: 1H-Indole, 2-[(3-nitrophenyl)thio]-
• CAS NO: 139461-67-9
• Molecular Formula: C14H10N2O2S
• Molecular Weight: 270.312
• Mol File: 139461-67-9.mol

Chemical Properties

• CAS DataBase Reference: 1H-Indole, 2-[(3-nitrophenyl)thio]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole, 2-[(3-nitrophenyl)thio]-(139461-67-9)
• EPA Substance Registry System: 1H-Indole, 2-[(3-nitrophenyl)thio]-(139461-67-9)

Safety Data

• Hazardous Substances Data: 139461-67-9(Hazardous Substances Data)

Upstream product

• 72496-79-8 3-<(3-nitrophenyl)thio>indole 

Relevant articles and documents

Acid-catalyzed Isomerization of 3-Indolyl Sulfides to 2-Indolyl Sulfides: First Synthesis of 3-Unsubstituted 2-(Arylthio)indoles. Evidence for a Complex intermolecular Process

The acid-catalyzed isomerization of 3-indolyl sulfides 1 to the corresponding 2-indolyl sulfides 4 provides the first synthesis of 3-unsubstituted 2-(arylthio)indoles, a hitherto unattainable class of compounds.When catalyzed by trifluoracetic acid, the isomerisation proceeds mainly via an intermolecular mechanism involving initial disproportionation to a 2,3-indolyl bis-sulfide 5 and an unsubstituted counterpart 6 followed by further interaction if these species to yield the rearranged isomer 4.A mechanism is proposed involving a role for the acid tn the sulfenyl-transfer steps.This type of process also occurs, to a lesser extent, in the polyphosphoric acid catalyzed isomerization.