139472-53-0

Upstream product

• 139472-45-0 S-tert-butyl (2R*,3R*)-2-ethyl-3-hydroxy-5-(trimethylsilyl)pent-4-ynethioate 
• 139472-52-9 S-tert-butyl (2R*,3S*)-3-amino-2-ethyl-5-(trimethylsilyl)pent-4-ynethioate 
• 103289-61-8 (3R*,4S*)-3-ethyl-4-(trimethylsilylethynyl)azetidin-2-one 
• 134250-80-9 (3R*,4S*)-3-ethyl-4-ethynylazetidin-2-one 
• 100-39-0 benzyl bromide 
• 134250-81-0 (3R*,4R*)-4-Ethenyl-3-ethyl-2-azetidinone 
• 139472-45-0 S-tert-butyl (2R*,3S*)-2-ethyl-3-hydroxy-5-(trimethylsilyl)pent-4-ynethioate 
• 139472-52-9 S-tert-butyl (2R*,3R*)-3-amino-2-ethyl-5-(trimethylsilyl)pent-4-ynethioate 
• 103289-61-8 (3R*,4R*)-3-ethyl-4-(trimethylsilylethynyl)azetidin-2-one 
• 134250-80-9 (3R*,4R*)-3-ethyl-4-ethynylazetidin-2-one 
• 134250-81-0 (3R*,4R*)-3-ethyl-4-vinylazetidin-2-one 

Downstream Products

• 139472-54-1 (3R*,4S*)-1-benzyl-3-ethyl-4-(2-hydroxyethyl)azetidin-2-one 
• 139472-54-1 (3R*,4R*)-1-benzyl-3-ethyl-4-(2-hydroxyethyl)azetidin-2-one 

Relevant academic research and scientific papers

Highly Diastereoselective Aldol Reactions of Cobalt-complexed and Uncomplexed Propynals with O-Silyl Ketene O,S-Ketals: Highly Stereoselective Divergent Formal Syntheses of the β-Lactam Antibiotics (+/-)-PS-5 and (+/-)-epi-PS-5

Treatment of a cobalt-complexed propynal derived from 3-trimethylsilylprop-2-ynal with O-silyl ketene O,S-ketals afforded the syn-aldol products exclusively, whereas the uncomplexed substrate 3-trimethylsilylprop-2-ynal provided the anti-ones exclusively

A highly diastereoselective aldol reaction of dicobalt hexacarbonyl propynal complex and uncomplexed propynal: A stereoselective divergent synthesis of (±)-PS-5 and (±)-6-Epi-PS-5

The aldol reaction of cobalt complexed propynal 1 with O-silyl ketene O,S-acetals 3 gave the syn-products exclusively, while the uncomplexed propynal 2, the corresponding anti-compounds. A successful application of these stereoselective reactions to a syn