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1394820-77-9

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  • N-(3-fluoro-4-((7-(2-hydroxy-2-Methylpropoxy)quinolin-4-yl)oxy)phenyl)-1,5-diMethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxaMide p-toluenesulfonate

    Cas No: 1394820-77-9

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  • NUTROCHEM- MANUFACTURE PLACE
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  • N-(3-Fluoro-4-((7-(2-hydroxy-2-methylpropoxy)quinolin-4-yl)oxy)phenyl)-1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide p-toluenesulfonate

    Cas No: 1394820-77-9

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  • ENAO Chemical Co, Limited
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  • N-(3-fluoro-4-((7-(2-hydroxy-2-Methylpropoxy)quinolin-4-yl)oxy)phenyl)-1,5-diMethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxaMide p-toluenesulfonate

    Cas No: 1394820-77-9

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  • N-(3-FLUORO-4-((7-(2-HYDROXY-2-METHYLPROPOXY)QUINOLIN-4-YL)OXY)PHENYL)-1,5-DIMETHYL-3-OXO-2-PHENYL-2,3-DIHYDRO-1H-PYRAZOLE-4-CARBOXAMIDE P-TOLUENESULFONATE

    Cas No: 1394820-77-9

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  • coolpharm Ltd
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1394820-77-9 Usage

Description

N-(3-fluoro-4-((7-(2-hydroxy-2-Methylpropoxy)quinolin-4-yl)oxy)phenyl)-1,5-diMethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide p-toluenesulfonate is a complex chemical compound that belongs to the class of carboxamides. It features a fluorine atom, a quinoline ring, a phenyl ring, and a pyrazole ring, which contribute to its unique structure and potential biological activity. N-(3-fluoro-4-((7-(2-hydroxy-2-Methylpropoxy)quinolin-4-yl)oxy)phenyl)-1,5-diMethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxaMide p-toluenesulfonate is often utilized in pharmacological and medical research as a promising drug candidate due to its potential therapeutic effects. The p-toluenesulfonate form of the compound is commonly employed for pharmaceutical formulation, enhancing its solubility and facilitating its use in drug discovery and development.

Uses

Used in Pharmaceutical Research and Development:
N-(3-fluoro-4-((7-(2-hydroxy-2-Methylpropoxy)quinolin-4-yl)oxy)phenyl)-1,5-diMethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide p-toluenesulfonate is used as a potential drug candidate in pharmaceutical research and development for its potential biological activity. Its complex structure and the presence of various functional groups make it a valuable compound for exploring new therapeutic avenues.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, this compound is used as a starting point for the design and synthesis of new drugs. Its unique structure and functional groups can be modified to create derivatives with improved pharmacological properties, such as increased potency, selectivity, and reduced side effects.
Used in Drug Discovery:
N-(3-fluoro-4-((7-(2-hydroxy-2-Methylpropoxy)quinolin-4-yl)oxy)phenyl)-1,5-diMethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide p-toluenesulfonate is used in drug discovery as a lead compound. Its synthesis, characterization, and study can provide valuable insights into its potential medical applications and therapeutic effects, guiding the development of new drugs with similar structures and activities.
Used in Pharmaceutical Formulation:
The p-toluenesulfonate form of the compound is used in pharmaceutical formulation to improve its solubility. This enhanced solubility facilitates the compound's incorporation into various drug delivery systems, such as tablets, capsules, and injectable solutions, ensuring its effective administration and bioavailability in the body.

Check Digit Verification of cas no

The CAS Registry Mumber 1394820-77-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,9,4,8,2 and 0 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1394820-77:
(9*1)+(8*3)+(7*9)+(6*4)+(5*8)+(4*2)+(3*0)+(2*7)+(1*7)=189
189 % 10 = 9
So 1394820-77-9 is a valid CAS Registry Number.

1394820-77-9Downstream Products

1394820-77-9Relevant articles and documents

CRYSTALLINE FORM OF A SUBSTITUTED QUINOLINE COMPOUND AND PHARMACEUTICAL COMPOSITIONS THEREOF

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Paragraph 0060; 0061, (2017/08/29)

The present invention relates to a crystalline form of N-(3-fluoro-4-((7-(2-hydroxy-2- methylpropoxy)quinolin-4-yl)oxy)phenyl)-1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro- 1H-pyrazole-4-carboxamide p-toluenesulfonate, the process for preparing the crystalline form thereof, and the pharmaceutical compositions comprising the crystalline form thereof. This invention also relates to a method of using such a crystalline form and pharmaceutical compositions comprising the crystalline form thereof in the treatment of hyperproliferative diseases in mammals, especially in humans.

SUBSTITUTED QUINOLINE COMPOUNDS AND METHODS OF USE

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Page/Page column 23, (2012/09/10)

The present invention provides novel substituted quinoline compounds, pharmaceutical acceptable salts and formulations thereof useful in modulating the protein tyrosine kinase activity, and in modulating cellular activities such as proliferation, differentiation, apoptosis, migration and invasion. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using the compositions in the treatment of hyperproliferative disorders in mammals, especially humans.

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