1394826-23-3

Basic information

• Product Name: 1-chloro-4-((1-methylcyclohexyl)ethynyl)benzene
• Synonyms: 1-chloro-4-((1-methylcyclohexyl)ethynyl)benzene
• CAS NO: 1394826-23-3
• Molecular Weight: 232.753
• Mol File: 1394826-23-3.mol

Chemical Properties

• CAS DataBase Reference: 1-chloro-4-((1-methylcyclohexyl)ethynyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-chloro-4-((1-methylcyclohexyl)ethynyl)benzene(1394826-23-3)
• EPA Substance Registry System: 1-chloro-4-((1-methylcyclohexyl)ethynyl)benzene(1394826-23-3)

Safety Data

• Hazardous Substances Data: 1394826-23-3(Hazardous Substances Data)

Upstream product

• 1394826-53-9 1-((4-chlorophenyl)ethynyl)-1λ³-benzo[d][1,2]iodaoxol-3(1H)-one 
• 82166-21-0 methyl cyclohexane 
• 1123-25-7 1-methyl-1-cyclohexanecarboxylic acid 

Relevant articles and documents

Directed alkynylation of unactivated C(sp3)-H bonds with ethynylbenziodoxolones mediated by DTBP

A general and efficient method for the direct alkynylation of unactivated C(sp3)-H bonds under metal-free conditions is described. The reaction performs smoothly under mild conditions and shows excellent functional-group tolerance. Initial mechanistic investigation indicates that the reaction may involve a radical pathway.

Silver-catalyzed decarboxylative alkynylation of aliphatic carboxylic acids in aqueous solution

C(sp3)-C(sp) bond formations are of immense interest in chemistry and material sciences. We report herein a convenient, radical-mediated and catalytic method for C(sp3)-C(sp) cross-coupling. Thus, with AgNO3 as the catalyst and K2S2O8 as the oxidant, various aliphatic carboxylic acids underwent decarboxylative alkynylation with commercially available ethynylbenziodoxolones in aqueous solution under mild conditions. This site-specific alkynylation is not only general and efficient but also functional group compatible. In addition, it exhibits remarkable chemo- and stereoselectivity.