1395080-72-4

Basic information

• Product Name: (3R,4R)-N-benzyl-3-fluorotetrahydro-2H-pyran-4-amine
• Synonyms: (3R,4R)-N-benzyl-3-fluorotetrahydro-2H-pyran-4-amine
• CAS NO: 1395080-72-4
• Molecular Weight: 209.264
• Mol File: 1395080-72-4.mol

Chemical Properties

• CAS DataBase Reference: (3R,4R)-N-benzyl-3-fluorotetrahydro-2H-pyran-4-amine(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,4R)-N-benzyl-3-fluorotetrahydro-2H-pyran-4-amine(1395080-72-4)
• EPA Substance Registry System: (3R,4R)-N-benzyl-3-fluorotetrahydro-2H-pyran-4-amine(1395080-72-4)

Safety Data

• Hazardous Substances Data: 1395080-72-4(Hazardous Substances Data)

Upstream product

• 28218-71-5 4,4-dimethoxytetrahydro-4H-pyran 
• 17327-22-9 4-methoxy-2,6-dihydropyran 
• 624734-19-6 3-fluorodihydro-2H-pyran-4(3H)-one 
• 100-46-9 benzylamine 

Downstream Products

• 1630906-37-4 (3R,4R)-3-fluorotetrahydro-2H-pyran-4-amine hydrochloride 

Relevant articles and documents

SUBSTITUTED AMINOPURINE COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH

Provided herein are Aminopurine Compounds having the following structures: wherein R1, R2, and R3 are as defined herein, compositions comprising an effective amount of an Aminopurine Compound, and methods for treating or preventing a cancer, for example, melanoma.

SERINE/THREONINE KINASE INHIBITORS

Compounds having the formula I wherein R2, X and Z as defined herein are inhibitors of ERK kinase. Also disclosed are compositions and methods for treating hyperproliferative disorders.

SERINE/THREONINE KINASE INHIBITORS

Compounds of Formula I or a stereoisomer, tautomer, prodrug or pharmaceutically acceptable salt thereof are provided, which are useful for the treatment of hyperproliferative, pain and inflammatory diseases. Methods of using compounds of Formula I or a stereoisomer, tautomer, prodrug or pharmaceutically acceptable salt thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.

QUINAZOLINE COMPOUNDS AS SERINE/THREONINE KINASE INHIBITORS

Compounds having the formula (I) wherein R1, R2, R3 and Ar as defined herein are inhibitors of ERK kinase. Also disclosed are compositions and methods for treating hyperproliferative disorders.