1395346-28-7 Usage
Description
Deferasirox Salicyloyl Ester is an impurity derived from Deferasirox (D228650), which is an orally active tridentate iron chelator. It plays a significant role in the pharmaceutical industry due to its association with iron chelation.
Uses
Used in Pharmaceutical Industry:
Deferasirox Salicyloyl Ester is used as an impurity in the development and formulation of Deferasirox, an orally active tridentate iron chelator. Its presence is crucial for the overall effectiveness and safety of the chelator, as it helps in the management of iron levels in the body, particularly in conditions like thalassemia and other iron-overload disorders.
The role of Deferasirox Salicyloyl Ester in the pharmaceutical industry is primarily to ensure the proper functioning and efficacy of Deferasirox as an iron chelator. By being a part of the formulation process, it contributes to the overall therapeutic outcomes of the treatment, making it an essential component in the management of iron-related health issues.
Check Digit Verification of cas no
The CAS Registry Mumber 1395346-28-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,9,5,3,4 and 6 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1395346-28:
(9*1)+(8*3)+(7*9)+(6*5)+(5*3)+(4*4)+(3*6)+(2*2)+(1*8)=187
187 % 10 = 7
So 1395346-28-7 is a valid CAS Registry Number.
1395346-28-7Relevant articles and documents
Synthesis and characterization of related substances of deferasirox, an iron (Fe3+) chelating agent
Rao, Vascuri Janardhana,Mukkanti, Kagga,Vekariya,Gupta, P. Badrinadh,Islam, Aminul
, p. 3200 - 3210 (2012/11/13)
Deferasirox is an orally active iron chelating agent, and during process development for deferasirox, we observed six related substances (impurities), namely deferasirox methyl ester, deferasirox salicylyl derivative, deferasirox ethyl ester, deferasirox methoxy carbonyl derivative, bis(salicyl)imide, and deferasirox-2-isomer. The present work describes the detection, origin, synthesis, and characterization of these related substances.
