1395395-63-7

Basic information

• Product Name: C₂₁H₂₁F₃N₄O
• CAS NO: 1395395-63-7
• Molecular Weight: 402.419
• Mol File: 1395395-63-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₁H₂₁F₃N₄O(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₁H₂₁F₃N₄O(1395395-63-7)
• EPA Substance Registry System: C₂₁H₂₁F₃N₄O(1395395-63-7)

Safety Data

• Hazardous Substances Data: 1395395-63-7(Hazardous Substances Data)

Upstream product

• 1395397-25-7 C₂₆H₂₉F₃N₄O₃ 
• 111373-03-6 2-(piperazin-1-yl)benzonitrile 
• 486460-00-8 (3R)-3-[(1,1-dimethylethoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic acid 

Relevant articles and documents

Dipeptidyl peptidase-4 inhibitor with β-amino amide scaffold: Synthesis, SAR and biological evaluation

Inhibitors of dipeptidyl peptidase-4 (DPP4) have been shown to be effective treatments for type 2 diabetes. Several series of β-amino amide containing piperazine derivatives have been prepared and evaluated as a inhibitor of DPP4. Finally compound 5m was selected for further evaluation.