1395397-83-7

Basic information

• Product Name: C₂₅H₂₉F₃N₄O₄
• CAS NO: 1395397-83-7
• Molecular Weight: 506.525
• Mol File: 1395397-83-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₅H₂₉F₃N₄O₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₅H₂₉F₃N₄O₄(1395397-83-7)
• EPA Substance Registry System: C₂₅H₂₉F₃N₄O₄(1395397-83-7)

Safety Data

• Hazardous Substances Data: 1395397-83-7(Hazardous Substances Data)

Upstream product

• 39639-98-0 piperazin-1-yl(pyridin-2-yl)methanone 
• 486460-00-8 (3R)-3-[(1,1-dimethylethoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic acid 
• 389628-28-8 tert-butyl 4-picolinoylpiperazine-1-carboxylate 

Relevant articles and documents

Dipeptidyl peptidase-4 inhibitor with β-amino amide scaffold: Synthesis, SAR and biological evaluation

Inhibitors of dipeptidyl peptidase-4 (DPP4) have been shown to be effective treatments for type 2 diabetes. Several series of β-amino amide containing piperazine derivatives have been prepared and evaluated as a inhibitor of DPP4. Finally compound 5m was selected for further evaluation.