139541-67-6

Upstream product

• 917-54-4 methyllithium 
• 139339-15-4 (1R,5S)-6,6-Dimethyl-4-<(1R)-1-methyl-3-butenyl>-3-(phenylsulfonyl)bicyclo<3.1.1>hept-3-en-2-one 
• 15681-48-8 lithium dimethylcuprate 
• 128261-64-3 (1R,5R)-6,6-Dimethyl-3-(phenylthio)bicyclo<3.1.1>hept-3-en-2-one 
• 139339-12-1 (1R,5S)-4-ethyl-6,6-dimethyl-3-(phenylsulfonyl)bicyclo<3.1.1>hept-3-en-2-one 
• 139339-17-6 (1R,3R,5S)-3-Allyl-4-<(E)-ethylidene>-6,6-dimethyl-3-(phenylsulfonyl)bicyclo<3.1.1>heptan-2-one 
• 151122-19-9 (1R,3R,4S,5R)-4-Ethyl-6,6-dimethyl-3-(phenylthio)bicyclo<3.1.1>heptan-2-one 
• 139339-14-3 (1R,5S)-4-Ethyl-6,6-dimethyl-3-(phenylthio)bicyclo<3.1.1>hept-3-en-2-one 
• 151053-00-8 (1R,3R,4S,5R)-4-But-3-enyl-6,6-dimethyl-3-phenylsulfanyl-bicyclo[3.1.1]heptan-2-one 
• 151053-01-9 (1R,5S)-4-But-3-enyl-6,6-dimethyl-3-phenylsulfanyl-bicyclo[3.1.1]hept-3-en-2-one 
• 151052-99-2 (1R,5S)-3-Benzenesulfonyl-4-but-3-enyl-6,6-dimethyl-bicyclo[3.1.1]hept-3-en-2-one 

Downstream Products

• 115356-18-8 kanshone A 

Relevant academic research and scientific papers

Extracyclic Stereocontrolled Alkylation of (1R,5S)-4-Ethyl-6,6-dimethyl-3-(phenylsulfonyl)bicyclohept-3-en-2-one. A Highly Stereocontrolled Synthesis of (-)-Kanshone A

(1R,5S)-4-Ethyl-6,6-dimethyl-3-(phenylsulfonyl)bicyclohept-3-en-2-one (7) was prepared from (+)-nopinone (1) in six steps and 70percent overall yield via (1R,5R)-6,6-dimethyl-3-(phenylthio)bicyclohept-3-en-2-one (2).Alkylation reactions of 7

A highly stereocontrolled synthesis of (-)-kanshone A

Described herein is the first and stereoselective synthesis of (-)-kanshone A (3), a nardosinan sesquiterpene, starting with enone 2.