139549-35-2Relevant academic research and scientific papers
Synthesis and evaluation of 2-pyridinone derivatives as HIV-1-specific reverse transcriptase inhibitors. 4. 3-[2-(Benzoxazol-2-yl)ethyl]-5-ethyl-6- methylpyridin-2(1H)-one and analogues
Hoffman,Smith,Rooney,Fisher,Wai,Thomas,Bamberger,Barnes,Williams,Jones,Olson,O'Brien,Goldman,Nunberg,Quintero,Schleif,Emini,Anderson
, p. 953 - 966 (2007/10/02)
A new series of potent specific 2-pyridinone reverse transcriptase (RT) inhibitors was developed based on the preliminary development lead 3- [(phthalimido)ethyl]-5-ethyl-6-methylpyridin-2(1H)-one (3), a non-nucleoside derivative which exhibited weak anti
