139564-53-7Relevant academic research and scientific papers
Antipicornavirus Activity of Tetrazole Analogues Related to Disoxaril
Diana, Guy D.,Cutcliffe, David,Volkots, Deborah L.,Mallamo, John P.,Bailey, Thomas R.,et al.
, p. 3240 - 3250 (2007/10/02)
A series of tetrazole analogues of Win 54954, a broad-spectrum antipicornavirus compound, has been synthesized to address the acid lability of the oxazoline ring of this series of compounds.The results of X-ray crystallography studies of several members o
CoMFA analysis of the interactions of antipicornavirus compounds in the binding pocket of human rhinovirus-14
Diana,Kowalczyk,Treasurywala,Oglesby,Pevear,Dutko
, p. 1002 - 1008 (2007/10/02)
A CoMFA analysis of eight compounds related to disoxaril whose X-ray structures bound to HRV-14 had been determined resulted in a strong positive correlation of activity with steric effects of the compounds, particularly toward the pore end of the compoun
