139575-15-8Relevant academic research and scientific papers
A convenient procedure for the catalytic asymmetric 1,3-dipolar cycloaddition of azomethine ylides and alkenes
Alemparte, Carlos,Blay, Gonzalo,Jorgensen, Karl Anker
, p. 4569 - 4572 (2005)
(Chemical Equation Presented) Silver fluoride and cinchona alkaloids catalyze the diastereo- and enantioselective 1,3-dipolar cycloaddition between azomethine ylides, generated from N-alkylideneglycine esters, and acrylates to give the corresponding endo-adducts. Azomethine ylides derived from aromatic and aliphatic aldehydes react in a highly diastereoselective reaction with good yields and enantioselectivities of the substituted pyrrolidines.
