1395922-82-3

Basic information

• Product Name: C₁₉H₁₉FN₆
• Synonyms: C₁₉H₁₉FN₆
• CAS NO: 1395922-82-3
• Molecular Weight: 350.398
• Mol File: 1395922-82-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₉H₁₉FN₆(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₉H₁₉FN₆(1395922-82-3)
• EPA Substance Registry System: C₁₉H₁₉FN₆(1395922-82-3)

Safety Data

• Hazardous Substances Data: 1395922-82-3(Hazardous Substances Data)

Upstream product

• 1395922-75-4 C₁₃H₁₅ClN₆ 
• 768-35-4 3-fluorophenylboronic acid 
• 1834-27-1 6-chloro-4-methyl-2H-pyridazin-3-one 

Relevant articles and documents

Identification of aminopyridazine-derived antineuroinflammatory agents effective in an Alzheimer's mouse model

Targeting neuroinflammation may be a new strategy to combat Alzheimer's disease. An aminopyridazine 1b previously reported as a novel antineuroinflammatory agent was considered to have a potential therapeutic effect for Alzheimer's disease. In this study, we further explored the chemical space to identify more potent antineuroinflammatory agents and validate their in vivo efficacy in an animal model. Compound 14 was finally identified as an effective agent with comparable in vivo efficacy to the marketed drug donepezil in counteracting spatial learning and working memory impairment in an Aβ-induced Alzheimer's mouse model.