1834-27-1

Basic information

• Product Name: 6-chloro-4-methyl-2H-pyridazin-3-one
• Synonyms: 6-chloro-4-methyl-2H-pyridazin-3-one;3(2H)-Pyridazinone, 6-chloro-4-Methyl-;6-Chloro-4-Methylpyridazin-3(2H)-one;6-Chloro-3-hydroxy-4-methylpyridazine;6-Chloro-4-methylpyridazin-3-ol, 6-Chloro-3-hydroxy-4-methyl-1,2-diazine;3-chloro-5-methyl-1H-pyridazin-6-one
• CAS NO: 1834-27-1
• Molecular Formula: C₅H₅ClN₂O
• Molecular Weight: 144.56
• Mol File: 1834-27-1.mol
• Article Data: 9

Chemical Properties

• Melting Point: 149-151 °C
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.45g/cm³
• Refractive Index: 1.608
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 9.84±0.60(Predicted)
• CAS DataBase Reference: 6-chloro-4-methyl-2H-pyridazin-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-chloro-4-methyl-2H-pyridazin-3-one(1834-27-1)
• EPA Substance Registry System: 6-chloro-4-methyl-2H-pyridazin-3-one(1834-27-1)

Safety Data

• Hazardous Substances Data: 1834-27-1(Hazardous Substances Data)

Usage

Description

6-chloro-4-methyl-2H-pyridazin-3-one is a heterocyclic organic compound characterized by a molecular formula of C5H5ClN2O. It features a pyridazine ring with a chloro and a methyl group attached, resulting in a white solid that is insoluble in water but soluble in organic solvents. 6-chloro-4-methyl-2H-pyridazin-3-one is widely utilized in pharmaceutical research and development as an intermediate for synthesizing biologically active compounds and has been explored for its potential therapeutic applications due to its pharmacological properties.

Uses

Used in Pharmaceutical Research and Development:
6-chloro-4-methyl-2H-pyridazin-3-one is used as a chemical intermediate for the synthesis of various biologically active compounds. Its unique structure and properties make it a valuable component in the development of new pharmaceuticals with potential therapeutic benefits.
Used in Drug Synthesis:
In the pharmaceutical industry, 6-chloro-4-methyl-2H-pyridazin-3-one is used as a key building block in the creation of novel drug molecules. Its presence in the molecular structure can contribute to the desired pharmacological activity and selectivity of the final drug product.
Used in Disease Treatment Research:
6-chloro-4-methyl-2H-pyridazin-3-one is used as a subject of investigation in research aimed at discovering new treatments for various diseases and disorders. Its pharmacological properties suggest potential applications in medicine, although further studies are required to fully understand its therapeutic potential and safety profile.
Used in Organic Chemistry:
In the field of organic chemistry, 6-chloro-4-methyl-2H-pyridazin-3-one serves as a versatile reagent and substrate for various chemical reactions. Its unique functional groups allow for a range of synthetic transformations, contributing to the advancement of organic chemistry and the development of new chemical compounds.
Used in Medicinal Chemistry:
6-chloro-4-methyl-2H-pyridazin-3-one is employed in medicinal chemistry as a template for designing new drugs with improved pharmacokinetic and pharmacodynamic properties. Its structural features can be modified to optimize drug-target interactions, leading to the development of more effective and safer therapeutic agents.

InChI:InChI=1/C5H5ClN2O/c1-3-2-4(6)7-8-5(3)9/h2H,1H3,(H,8,9)

Upstream product

• 19064-64-3 3,6-dichloro-4-methylpyridazine 
• 616-02-4 citraconic acid anhydride 
• 5754-18-7 4-methyl-1,2-dihydropyridazine-3,6-dione 
• 89466-38-6 6-chloro-3-methoxy-4-methylpyridazine 

Downstream Products

• 1395922-81-2 C₂₀H₂₂N₆O 
• 886208-65-7 Minozac 
• 1395922-86-7 C₂₀H₂₂N₆O 
• 1395922-85-6 C₂₀H₂₂N₆ 
• 1395922-84-5 C₁₉H₁₉FN₆ 
• 1395922-83-4 C₂₀H₁₉F₃N₆ 
• 1395922-82-3 C₁₉H₁₉FN₆ 
• 1114573-48-6 (S)-3-((S)-1-(4-(1,5-dimethyl-6-oxo-1,6-dihydropyridazin-3-yl)phenyl)ethyl)-6-(2-hydroxy-2-methylpropyl)-6-phenyl-1,3-oxazinan-2-one 

Relevant articles and documents

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