139628-15-2Relevant academic research and scientific papers
Total chiral synthesis of azole antifungals via α-hydroxylation of ketones
Gala, Dinesh,DiBenedetto, Donald J.,Mergelsberg, Ingrid,Kugelman, Max
, p. 8117 - 8120 (1996)
The use of camphorsulfonyl oxaziridines for the preparation of 2',4'-difluoro-(R)-2-hydroxypropiophenone, (2), a key intermediate for the synthesis of azole antifungals Sch 42427 and ER-30346 (1) in excellent enantiomeric excess and high chemical yield is described.
