Tetrahedron Letters p. 8117 - 8120 (1996)
Update date:2022-08-03
Topics:
Gala, Dinesh
DiBenedetto, Donald J.
Mergelsberg, Ingrid
Kugelman, Max
The use of camphorsulfonyl oxaziridines for the preparation of 2',4'-difluoro-(R)-2-hydroxypropiophenone, (2), a key intermediate for the synthesis of azole antifungals Sch 42427 and ER-30346 (1) in excellent enantiomeric excess and high chemical yield is described.
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