1396312-89-2Relevant academic research and scientific papers
Fluorescence labeling of amino acids and peptides with 7-aminocoumarins
Wirtz, Lisa,Auerbach, Dagmar,Jung, Gregor,Kazmaier, Uli
, p. 2005 - 2012 (2012/08/27)
Pechmann condensation is a straightforward protocol for the synthesis of alkynyl- and azido-substituted 7-(dialkylamino)coumarins, which can be coupled to amino acid and peptide derivatives by copper-catalyzed [3+2]-cycloaddition (click reaction) in high yield. This allows the introduction of these efficient fluorescence labels into biologically relevant molecules. Georg Thieme Verlag Stuttgart ? New York.
