1396318-54-9

Basic information

• Product Name: (S)-3-((1'R,2'S,3R,7a'R)-5-nitro-1-ethyl-2-oxo-1'-phenyl-1',2',5',6',7',7a'-hexahydrospiro[indoline-3,3'-pyrrolizin]-2'-ylcarbonyl)-4-phenyloxazolidin-2-one
• Synonyms: (S)-3-((1'R,2'S,3R,7a'R)-5-nitro-1-ethyl-2-oxo-1'-phenyl-1',2',5',6',7',7a'-hexahydrospiro[indoline-3,3'-pyrrolizin]-2'-ylcarbonyl)-4-phenyloxazolidin-2-one
• CAS NO: 1396318-54-9
• Molecular Weight: 566.613
• Mol File: 1396318-54-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-3-((1'R,2'S,3R,7a'R)-5-nitro-1-ethyl-2-oxo-1'-phenyl-1',2',5',6',7',7a'-hexahydrospiro[indoline-3,3'-pyrrolizin]-2'-ylcarbonyl)-4-phenyloxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-((1'R,2'S,3R,7a'R)-5-nitro-1-ethyl-2-oxo-1'-phenyl-1',2',5',6',7',7a'-hexahydrospiro[indoline-3,3'-pyrrolizin]-2'-ylcarbonyl)-4-phenyloxazolidin-2-one(1396318-54-9)
• EPA Substance Registry System: (S)-3-((1'R,2'S,3R,7a'R)-5-nitro-1-ethyl-2-oxo-1'-phenyl-1',2',5',6',7',7a'-hexahydrospiro[indoline-3,3'-pyrrolizin]-2'-ylcarbonyl)-4-phenyloxazolidin-2-one(1396318-54-9)

Safety Data

• Hazardous Substances Data: 1396318-54-9(Hazardous Substances Data)

Upstream product

• 141209-95-2 (4S)-4-phenyl-3-[(2E)-3-phenylprop-2-enoyl]-1,3-oxazolidin-2-one 

Downstream Products

• 1396318-63-0 (1'R,2'S,3R,7a'R)-1-ethyl-5-nitro-2-oxo-1'-phenyl-1',2',5',6',7',7a'-hexahydrospiro[indoline-3,3'-pyrrolizine]-2'-carboxylic acid 

Relevant articles and documents

Synthesis of new enantiomerically pure spirooxindolopyrrolizidines via a three-component asymmetric 1,3-dipolar cycloaddition reaction of azomethine ylides derived from isatin

An efficient, one-pot, three-component procedure for the synthesis of a small library of new chiral spirooxindolopyrrolizidines with high regio-, diastereo-, and enantioselectivity, from the 1,3-dipolar cycloaddition of azomethine ylides and optically active cinnamoyl oxazolidinone is described. The process occurs at room temperature in aqueous ethanol as a green solvent and in the absence of any Lewis acids. The oxazolidinone chiral auxiliary is removed in a non-destructive manner. The reaction mechanism is discussed on the basis of the assignment of the absolute configuration of the cycloadducts, and on theoretical calculations.