139678-43-6

Basic information

• Product Name: 1-cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydro-3-quinoline carboxylic acid (O₃,O⁴)bis(acyloxy-O)borate
• Synonyms: 1-cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydro-3-quinoline carboxylic acid (O₃,O⁴)bis(acyloxy-O)borate
• CAS NO: 139678-43-6
• Molecular Weight: 423.135
• Mol File: 139678-43-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydro-3-quinoline carboxylic acid (O₃,O⁴)bis(acyloxy-O)borate(CAS DataBase Reference)
• NIST Chemistry Reference: 1-cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydro-3-quinoline carboxylic acid (O₃,O⁴)bis(acyloxy-O)borate(139678-43-6)
• EPA Substance Registry System: 1-cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydro-3-quinoline carboxylic acid (O₃,O⁴)bis(acyloxy-O)borate(139678-43-6)

Safety Data

• Hazardous Substances Data: 139678-43-6(Hazardous Substances Data)

Upstream product

• 4887-24-5 triacetoxyborane 
• 112811-71-9 ethyl 8-methoxy-1-cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylate 

Downstream Products

• 186826-86-8 moxifloxacin hydrochloride 
• 133762-22-8 (S)-1-cyclopropyl-1,4-dihydro-7-[2-(N,N-dimethylaminomethyl)morpholino]-6-fluoro-8-methoxy-4-oxoquinoline-3-carboxylic acid 

Relevant articles and documents

Preparation method of moxifloxacin hydrochloride chelate

The invention provides a preparation method of moxifloxacin hydrochloride chelate, and belongs to the technical field of heterocyclic compound preparation. The preparation method comprises the following steps: keeping excessive acetic acid, adding trimethyl borate into the acetic acid, and reacting at 110-120 DEG C; after the reaction is finished, cooling, adding gatifloxacin intermediate, heatingto 110-120 DEG C after the addition is finished, keeping on reacting; recovering the fraction under reduced pressure until the reaction is finished, and recovering the solvent until the solvent is dry to obtain the chelate. The method has the advantages of simple process, economy, environmental friendliness and high product purity.