139680-99-2Relevant academic research and scientific papers
A one-pot synthesis of 2,2-difluorovinyl carbonyl compounds from 2,2,2-trifluoroethyl p-toluenesulfonate via 2,2-difluorovinylboranes
Ichikawa,Hamada,Sonoda,Kobayashi
, p. 337 - 340 (2007/10/02)
2,2,2-Trifluoroethyl p-toluenesulfonate is treated with butyllithium and trialkylboranes successively to generate 1-alkyl-2,2-difluorovinylboranes, which in turn react with acyl chlorides or chlorides or chloroformates in the presence of cuprous iodide to affort 2,2-difluorovinyl carbonyl compounds in good yields.
