139681-39-3Relevant articles and documents
Hypoglycemic prodrugs of 4-(2,2-dimethyl-1-oxopropyl)benzoic acid
Aicher, Thomas D.,Bebernitz, Gregory R.,Bell, Philip A.,Brand, Leonard J.,Dain, Jeremy G.,Deems, Rhonda,Fillers, William S.,Foley, James E.,Knorr, Douglas C.,Nadelson, Jeffrey,Otero, Dario A.,Simpson, Ronald,Strohschein, Robert J.,Young, Douglas A.
, p. 153 - 163 (2007/10/03)
SAH 51-641 (1) is a potent hypoglycemic agent, which acts by inhibiting hepatic gluconeogenesis. It is a prodrug of 4-(2,2-dimethyl-1- oxopropyl)benzoic acid (2) and 4-(2,2-dimethyl-1-hydroxypropyl)benzoic acid (3), which sequester coenzyme A (CoA) in the
Process for preparing substituted N-oxy-imidic acid derivatives
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, (2008/06/13)
N-oxy substituted imidic acid derivative of the formula STR1 where R1, R2 and R3 are alkyl and aryl substituents, which are useful as antidiabetic and hypolipidemic agents are prepared by the following procedure: STR2 wher