32018-31-8

Basic information

• Product Name: 4-(2,2-dimethyl-1-oxopropyl)benzoic acid
• Synonyms: 4-(2,2-dimethyl-1-oxopropyl)benzoic acid
• CAS NO: 32018-31-8
• Molecular Formula: C₁₂H₁₄O₃
• Molecular Weight: 206.23776
• Mol File: 32018-31-8.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(2,2-dimethyl-1-oxopropyl)benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2,2-dimethyl-1-oxopropyl)benzoic acid(32018-31-8)
• EPA Substance Registry System: 4-(2,2-dimethyl-1-oxopropyl)benzoic acid(32018-31-8)

Safety Data

• Hazardous Substances Data: 32018-31-8(Hazardous Substances Data)

Upstream product

• 69001-49-6 α,α-dibromo-4-pivaloyl toluene 
• 62985-52-8 ethyl 4-(2,2-dimethylpropanoyl)benzoate 
• 104-82-5 4-Methylbenzyl chloride 
• 30314-44-4 2,2-dimethyl-1-(4-methylphenyl)-1-propanone 
• 24797-40-8 4-methyl-1-(2,2-dimethylpropyl)benzene 
• 65687-52-7 4-(2,2-dimethylpropyl)benzoic acid 

Downstream Products

• 220764-79-4 methyl 4-(2,2-dimethyl-1-oxopropyl)benzoate 
• 139681-39-3 4-(2,2-dimethyl-1-oxopropyl)-benzoyl chloride 
• 163089-77-8 4-carboxy-α-(1,1-dimethylethyl)benzenemethanol 
• 139681-18-8 4-pivaloylbenzoyl-N-methoxy-4-pivaloylbenzimidate 
• 167759-93-5 4-(2,2-dimethyl-1-oxopropyl)-benzoic acid, (2-diethylamino-2-oxo) ethyl ester 
• 62985-52-8 ethyl 4-(2,2-dimethylpropanoyl)benzoate 
• 1094044-96-8 sodium 4-(2,2-dimethylpropanoyl)benzoate 
• 157465-52-6 4-(2,2-dimethyl-propionyl)-N-{2-[(4-methoxy-phenyl)-diphenyl-methoxy]-ethoxy}-benzamide 
• 220764-70-5 {bis-[4-(2,2-dimethyl-propionyl)-benzoyl]-amino}-acetic acid tert-butyl ester 

Relevant articles and documents

NOVEL IMIDE DERIVATIVES AND USE THEREOF AS MEDICINE

Provided is a novel low-molecular-weight compound that suppresses production of induction type MMPs, particularly MMP-9, rather than production of hemostatic type MMP-2. The present invention relates to a compound represented by the following formula (I): wherein each symbol is as described in the DESCRIPTION. The compound has a selective MMP-9 production suppressive action, and is useful as a drug for the prophylaxis and/or treatment of autoimmune diseases such as rheumatoid arthritis and the like, inflammatory bowel diseases (ulcerative colitis, Crohn's disease) or osteoarthritis.

Hypoglycemic prodrugs of 4-(2,2-dimethyl-1-oxopropyl)benzoic acid

SAH 51-641 (1) is a potent hypoglycemic agent, which acts by inhibiting hepatic gluconeogenesis. It is a prodrug of 4-(2,2-dimethyl-1- oxopropyl)benzoic acid (2) and 4-(2,2-dimethyl-1-hydroxypropyl)benzoic acid (3), which sequester coenzyme A (CoA) in the