1397-94-0 Usage
Description
Antimycin A is a complex of related macrocyclic lactones, predominantly A1 to A4, isolated from several species of Streptomyces. It is a crystalline solid with potent antifungal activity and is known for its ability to bind to cytochrome C reductase at the Qi site, inhibiting the oxidation of ubiquinol to ubiquinone. Antimycin A has over 20 known analogues and is widely used as a bioprobe of respiration.
Uses
Used in Antifungal Applications:
Antimycin A is used as an antifungal agent for its potent antifungal activity, particularly against various fungal species. It is effective in controlling fungal infections and is registered as a pesticide in the U.S.
Used in Agricultural Industry:
Antimycin A is used as a fungicide, piscicide, and potentially as an insecticide and miticide in the agricultural industry. As a U.S. EPA restricted Use Pesticide (RUP), it plays a crucial role in controlling pests and maintaining crop health.
Used in Biochemical Research:
Antimycin A is used as a bioprobe of respiration in biochemical research. It helps scientists study the specific sites of reactive oxygen species production in mitochondria and their relationship with local oxidative stress induced by exercise.
Used in Pharmaceutical Industry:
Antimycin A is used in the pharmaceutical industry for its antiviral properties and its ability to interfere with cytochrome oxidation. It has potential applications in the development of new drugs targeting viral infections and other related conditions.
Fire Hazard
When heated to decomposition, ANTIMYCIN A emits toxic fumes of oxides of nitrogen.
Trade name
FINTROL?; VIROSIN?
Safety Profile
Poison by ingestion,intraperitoneal, subcutaneous, and intravenous routes.When heated to decomposition it emits toxic fumes ofNOx.
Potential Exposure
Specific uses for antimycin A were
not found, however, antimycin A1, and antimycin A3 are
reported to be antibiotic substances produced by streptomyces
for use as a fungicide, possible insecticide and miticide.
Registered as a pesticide in the U.S.
Shipping
UN2811 Toxic solids, organic, n.o.s., Hazard
Class: 6.1; Labels: 6.1-Poisonous materials, Technical
Name Required.
Check Digit Verification of cas no
The CAS Registry Mumber 1397-94-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,3,9 and 7 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1397-94:
(6*1)+(5*3)+(4*9)+(3*7)+(2*9)+(1*4)=100
100 % 10 = 0
So 1397-94-0 is a valid CAS Registry Number.
InChI:InChI=1/C28H40N2O9/c1-6-7-8-9-11-20-25(39-22(32)14-16(2)3)18(5)38-28(36)23(17(4)37-27(20)35)30-26(34)19-12-10-13-21(24(19)33)29-15-31/h10,12-13,15-18,20,23,25,33H,6-9,11,14H2,1-5H3,(H,29,31)(H,30,34)/t17-,18+,20-,23?,25+/m1/s1