139710-81-9Relevant academic research and scientific papers
Tandem Dehydrogenation/Oxidation/Oxidative Cyclization Approach to Wrightiadione and Its Derivatives
Jeong, Yujeong,Moon, Youngtaek,Hong, Sungwoo
, p. 3252 - 3255 (2015/07/15)
Wrightiadione contains a unique tetracyclic isoflavone moiety and has been shown to exhibit a broad range of biological activities. An efficient and straightforward synthetic method for generating the molecular complexity of wrightiadione was developed th
Hetero-ring Lithiation of N-Methyl-4-quinolone and N-Methylquinoline-4-thione
Alvarez, Mercedes,Salas, Marisa,Rigat, Lluis,Veciana, Ana de,Joule, John A.
, p. 351 - 356 (2007/10/02)
Lithiation of 1-methyl-4-quinolone and 1-methylquinoline-4-thione with lithium diisopropylamide (LDA) at -78 deg C takes place at C-2.The resulting lithio-species react with a variety of electrophiles to give 2-substituted-4-quinolones and -quinolines-4-thiones respectively. 1-Methylquinoline-4-thione is easily converted into 1-methyl-4-quinolone in protic solution.
