139727-36-9Relevant academic research and scientific papers
Structure-Activity Relationships of the Antimalarial Agent Artemisinin. 1. Synthesis and Comparative Molecular Field Analysis of C-9 Analogs of Artemisinin and 10-Deoxoartemisinin
Avery, Mitchell A.,Gao, Fenglan,Chong, Wesley K. M.,Mehrotra, Sanjiv,Milhous, Wilbur K.
, p. 4264 - 4275 (1993)
A series of C-9 β-substituted artemisinin analogs (2-21) were synthesized via dianion alkylation of the total synthetic intermediate 57 followed by subsequent ozonolysis/acidification, or by alkylation of the enolate derived from (+)-9-desmethylartemisini
