1397689-63-2Relevant academic research and scientific papers
Metal-free iodine(III)-promoted direct intermolecular C-H amination reactions of acetylenes
Souto, Jose A.,Becker, Peter,Iglesias, Alvaro,Muniz, Kilian
, p. 15505 - 15511 (2012)
A direct metal-free amination of arylalkynes has been developed, which proceeds by reaction of the terminal alkyne with the hypervalent iodine reagent PhI(OAc)NTs2 within a single-step operation. This unprecedented intermolecular C-H to C-N bond conversion provides rapid access to the important class of ynamides. In addition to the title reaction, the related transformation between alkylated alkynes and the iodine(III) reagent is also discussed.
