1397705-06-4Relevant academic research and scientific papers
Convenient method for the synthesis of phosphoramidite non-nucleotide inserts for preparation of functionalized oligonucleotides
Kupryushkin,Pyshnyi
, p. 662 - 666 (2013/02/25)
A simple approach to the synthesis of amidophosphite synthons of achiral non-nucleotide inserts using 4-(2-(4,4'-dimethoxytrityloxy)ethyl)morpholine-2,3- dione as a backbone of key precursor was suggested. Non-nucleotide synthons were synthesized using this approach that were suitable for synthesis of acridine-containing oligonucleotide derivatives, as well as oligonucleotides with branched carbohydrate-phosphate backbone. Pleiades Publishing, Ltd., 2012.
