1397956-73-8

Basic information

• Product Name: 3-((cyclohexyl(2-hydroxyethyl)amino)methyl)-5-(cyclohexylmethoxy)-4H-chromen-4-one
• Synonyms: 3-((cyclohexyl(2-hydroxyethyl)amino)methyl)-5-(cyclohexylmethoxy)-4H-chromen-4-one
• CAS NO: 1397956-73-8
• Molecular Weight: 413.557
• Mol File: 1397956-73-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-((cyclohexyl(2-hydroxyethyl)amino)methyl)-5-(cyclohexylmethoxy)-4H-chromen-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-((cyclohexyl(2-hydroxyethyl)amino)methyl)-5-(cyclohexylmethoxy)-4H-chromen-4-one(1397956-73-8)
• EPA Substance Registry System: 3-((cyclohexyl(2-hydroxyethyl)amino)methyl)-5-(cyclohexylmethoxy)-4H-chromen-4-one(1397956-73-8)

Safety Data

• Hazardous Substances Data: 1397956-73-8(Hazardous Substances Data)

Upstream product

• 2842-38-8 cyclohexyl(2-(hydroxy)ethyl)amine 
• 1229444-25-0 5-(cyclohexylmethoxy)-4-oxo-4H-chromene-3-carbaldehyde 

Relevant articles and documents

Novel hydroxyethylaminomethylchromenones derivatives which inhibit the interleukin-5 activity

The present invention relates to a novel hydroxyethylaminomethylchromenone derivative, a manufacturing method thereof, or a pharmaceutical composition including the hydroxyethylaminomethylchromenone derivative for preventing or treating allergic diseases. Since the hydroxyethylaminomethylchromenone derivative is low-molecular, non-peptide-based material, the derivative has no non-specific reaction for proteins unlike existing treating agents known for allergic diseases. In addition, the hydroxyethylaminomethylchromenone derivative of the present invention is an amine-form compound, and thereby, remarkably increasing water solubility compared to the existing hydroxyethylaminomethylchromenone derivatives manufactured, as well as having higher effects of inhibiting interleukin-5 activities due to difference in chemical structures, such that the compound of the present invention can be effectively used as an inhibitor for allergic diseases. Furthermore, since the existing hydroxyethylaminomethylchromenone derivatives have a chiral center, it produces inconvenience as it requires to check whether the an isomer exists or not. However, the present invention solves the inconvenience so as to have an advantage of being capable of easily manufacturing a compound. [Reference numerals] (AA,CC) Compound 3d; (BB,DD) Compound 4i