1398382-77-8

Basic information

• Product Name: allyl (2S,3R)-3-methyl-2-phenylindoline-1-carboxylate
• CAS NO: 1398382-77-8
• Molecular Weight: 293.365
• Mol File: 1398382-77-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: allyl (2S,3R)-3-methyl-2-phenylindoline-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: allyl (2S,3R)-3-methyl-2-phenylindoline-1-carboxylate(1398382-77-8)
• EPA Substance Registry System: allyl (2S,3R)-3-methyl-2-phenylindoline-1-carboxylate(1398382-77-8)

Safety Data

• Hazardous Substances Data: 1398382-77-8(Hazardous Substances Data)

Upstream product

• 721968-93-0 3-methoxyphenyl allyl carbonate 

Relevant articles and documents

Stereoselective synthesis of 2,3-disubstituted indoline diastereoisomers by chemoenzymatic processes

Racemic indolines including a variety of structural motifs such as C-2 and C-3 substitutions (alkyl or aryl), cis/trans relative stereochemistry and functionalization of the aromatic ring (fluoro, methyl or methoxy groups) have been efficiently prepared through Fischer indolization and subsequent diastereoselective reduction of the unprotected indoles. Combination of Candida antarctica lipase type A and allyl 3-methoxyphenyl carbonate has been identified as the best tandem for their kinetic resolutions, observing excellent stereodiscriminations for most of the tested indolines.