1398547-93-7

Upstream product

• 563-70-2 bromonitromethane 
• 32085-88-4 3,5-difluorobenzaldehyde 

Downstream Products

• 1398547-80-2 (S)-2-((S)-2-(3,5-difluorophenyl)-2-(methoxymethoxy)acetamido)-N-((S)-5-methyl-6-oxo-6,7-dihydro-5Hdibenzo[b,d]azepin-7-yl)propanamide 
• 1398547-77-7 (S)-2-((S)-2-(3,5-difluorophenyl)-2-(methoxymethoxy)acetamido)propanoic acid 
• 1398547-76-6 (S)-isopropyl 2-((S)-2-(3,5-difluorophenyl)-2-(methoxymethoxy)acetamido)propanoate 

Relevant academic research and scientific papers

Enantioselective synthesis of α-oxy amides via Umpolung Amide Synthesis

α-Oxy amides are prepared through enantioselective synthesis using a sequence beginning with a Henry addition of bromonitromethane to aldehydes and finishing with Umpolung Amide Synthesis (UmAS). Key to high enantioselection is the finding that ortho-iodo