1398566-69-2Relevant articles and documents
Method for preparation of chiral chlorooxindole derivatives
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Paragraph 0046; 0047; 0054; 0086; 0087; 0088, (2016/10/24)
Derivatives of chiral chloro jade poet pebble is disclosure is manufacturing method. The present invention refers to, chiral organic catalyst in the presence, (E)-2-( (E)-2-arylnitroethene [...]) isoindoline chloro 3-derivatives and-2-on (3-chloroindoline-2-one) derivatives characterized in that reaction.
Organocatalytic asymmetric synthesis of 3-chlorooxindoles bearing adjacent quaternary-tertiary centers
Noole, Artur,Jaerving, Ivar,Werner, Franz,Lopp, Margus,Kanger, Tonis,Malkov, Andrei
supporting information, p. 4922 - 4925,4 (2012/12/12)
A new methodology was developed for the synthesis of enantiomerically enriched 3,3-disubstituted 3-chlorooxindoles 3 via a Michael addition of 3-chloroxindoles to nitroolefins 2, catalyzed by chiral squaramide 10. Products with adjacent quaternary-tertiary centers were isolated in excellent yields (up to 99%), high diastereoselectivities (up to 11:1), and enantiomeric purities (up to 92%). This is the first example where 3-chloroxoindoles 1 have been used as nucleophiles in a highly stereoselective organocatalytic reaction.
Organocatalytic asymmetric synthesis of 3-chlorooxindoles bearing adjacent quaternary-tertiary centers
Noole, Artur,J?rving, Ivar,Werner, Franz,Lopp, Margus,Malkov, Andrei,Kanger, T?nis
supporting information, p. 4922 - 4925 (2013/01/15)
A new methodology was developed for the synthesis of enantiomerically enriched 3,3-disubstituted 3-chlorooxindoles 3 via a Michael addition of 3-chloroxindoles to nitroolefins 2, catalyzed by chiral squaramide 10. Products with adjacent quaternary-tertiar
