1398743-40-2Relevant academic research and scientific papers
Palladium-Catalyzed [5+1] Annulation of 2-(1-Arylvinyl) Anilines and α-Diazocarbonyl Compounds toward Multi-functionalized Quinolines
Zhu, Jiawei,Hu, Weiming,Sun, Song,Yu, Jin-Tao,Cheng, Jiang
, p. 3725 - 3728 (2017)
A palladium-catalyzed [5+1] annulation of 2-(1-arylvinyl) anilines and α-diazocarbonyl compounds has been developed, affording a series of multi-functionalized quinolines in moderate to good yields. This procedure proceeded with the sequential insertion o
Manganese(ii)-catalysed dehydrogenative annulation involving C-C bond formation: highly regioselective synthesis of quinolines
Wang, Chengniu,Yang, Jinfei,Meng, Xiao,Sun, Yufeng,Man, Xuyan,Li, Jinxia,Sun, Fei
supporting information, p. 4474 - 4478 (2019/04/05)
An inexpensive nontoxic manganese(ii)-catalysed dehydrogenative annulation was developed for C-C bond formation. The reaction showed high selectivity and efficiency across a broad substrate scope. Remarkably simple conditions and the ability to conduct gram-scale synthesis underscore this method's utility. To demonstrate the potential of this approach, we tested the drug effects of compound 3n, which showed activity for blocking vascular development. The results of this study will be important for the treatment of eye diseases and tumors caused by vascular proliferation.
Synthesis of substituted quinolines by iron-catalyzed oxidative coupling reactions
Liu, Peng,Li, Yuxi,Wang, Haiyu,Wang, Zhiming,Hu, Xianming
supporting information, p. 6654 - 6656,3 (2012/12/13)
A simple and efficient method has been developed for the synthesis of quinoline derivatives from N-alkyl anilines and alkynes or alkenes by iron-catalyzed oxidative coupling reactions. A variety of substituted quinolines are prepared in good to excellent yields.
Palladium-catalyzed sequential formation of C-C bonds: Efficient assembly of 2-substituted and 2,3-disubstituted quinolines
Ji, Xiaochen,Huang, Huawen,Li, Yibiao,Chen, Huoji,Jiang, Huanfeng
supporting information; experimental part, p. 7292 - 7296 (2012/08/28)
A series of substituted quinolines was prepared from arylamines, aldehydes, and terminal olefins (see scheme). The palladium-catalyzed sequential formation of C-C bonds proceeds smoothly with both electron-deficient and electron-rich olefins. When acrylic acid is used as terminal olefin, decarboxylation occurs to provide 2-substituted quinolines. Copyright
