1399085-99-4Relevant academic research and scientific papers
A convenient and efficient C-OH bond activation, PdCl2(PPh3)2catalyzed, C-C bond formation of tautomerizable quinolinones with the aid of BOP reagent and boronic acids
Kumar, Yadavalli Suneel,Dasaradhan,Prabakaran, Kamalakannan,Nawaz Khan, Fazlur-Rahman,Jeong, Euh Duck,Chung, Eun Hyuk,Kim, Hyun Gyu
, p. 40259 - 40268 (2015/02/05)
An efficient, highly chemoselective PdCl2(PPh3)2catalyzed, C-C bond formation of tautomerizable quinolinones with various boronic acids via C-OH bond activation using benzotriazol-1-yloxytris(dimethylamino) phosphonium hexafluorophosphate (BOP) reagent in the presence of K2CO3/1,4-dioxane system under aqueous condition, leads to the formation of functionalized quinolines in excellent yields, which offers great utility advantages in the synthesis of interesting compounds. This journal is
An organocatalytic cascade approach toward polysubstituted quinolines and chiral 1,4-dihydroquinolines-unanticipated effect of N-protecting groups
Zhang, Xinshuai,Song, Xixi,Li, Hao,Zhang, Shilei,Chen, Xiaobei,Yu, Xinhong,Wang, Wei
supporting information; experimental part, p. 7282 - 7286 (2012/09/08)
A matter of protection: The outcome of a divergent organocatalytic aza-Michael/aldol cascade process toward quinolines and 1,4-dihydroquinolines depends on the choice of the N-protecting group (see scheme; TEA=triethylamine, TMS=trimethylsilyl). Use of an electron-donating sulfonyl group results in an unanticipated aza-Michael/aldol/aromatization cascade to give polysubstituted quinolines (right). In contrast, chiral 1,4-dihydroquinolines are obtained with an electron-withdrawing sulfonyl group (left). Copyright
