1399331-04-4Relevant academic research and scientific papers
Cyclometallation of arylimines and nitrogen-containing heterocycles via room-temperature C-H bond activation with arene ruthenium(ii) acetate complexes
Li, Bin,Roisnel, Thierry,Darcel, Christophe,Dixneuf, Pierre H.
, p. 10934 - 10937 (2012)
The reaction of [RuCl2(p-cymene)]2 with arylimines and 4 equiv. of KOAc in methanol at room temperature produces stable (N^C)-cyclometallated ruthenium(ii) complexes via C-H bond activation/ deprotonation. This method can be applied
Cycloruthenation of aryl imines and N-heteroaryl benzenes via C-H bond activation with Ru(II) and acetate partners
Li, Bin,Darcel, Christophe,Roisnel, Thierry,Dixneuf, Pierre H.
, p. 200 - 209 (2015/09/01)
The reaction of arylimines with [RuCl2(p-cymene)]2 and 4 equiv. of KOAc at room temperature in methanol leads to the formation of N-Ru-C cycloruthenates RuCl(arylimine-kC,N)(p-cymene) 3a-3d via ortho C-H activation/deprotonation by acetate. The presence of the stable Ru-Cl bond rather than a labile Ru-OAc bond is crucial for the isolation of the complexes. This preparative method of cyclometallates was applied to 2-phenyloxazoline, and benzo[h]quinoline and to the improved synthesis of 2-phenylpyridine and 1-phenylpyrazole derivatives. The molecular structures of three cycloruthenates are reported.
