2743-00-2

Usage

Uses

Used in Dye and Pigment Production:
Benzenamine, 4-methoxy-N-(1-phenylethylidene)is used as a key intermediate in the production of dyes and pigments. Its chemical structure contributes to the color and stability of these products, making it an essential component in the formulation of various dyes and pigments for different applications.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, Benzenamine, 4-methoxy-N-(1-phenylethylidene)is utilized as a building block in the synthesis of various pharmaceuticals. Its unique structure allows for the development of new drugs with potential therapeutic effects, contributing to the advancement of medicinal chemistry.
Used in Organic Compound Synthesis:
Benzenamine, 4-methoxy-N-(1-phenylethylidene)is also employed in the synthesis of other organic compounds. Its reactivity and solubility in organic solvents make it a versatile component in the preparation of a wide range of organic molecules for various applications in the chemical industry.

Upstream product

• 104-94-9 4-methoxy-aniline 
• 98-86-2 acetophenone 
• 536-74-3 phenylacetylene 
• 126522-56-3 4-methoxy-N-(1-phenylethyl)aniline 
• 100-42-5 styrene 
• 20102-12-9 2-hydroxy-2-phenylpropionitrile 
• 36714-99-5 N-(1-(4-bromophenyl)ethylidene)-4-methoxybenzenamine 
• 100-58-3 phenylmagnesium bromide 
• 98-81-7 1-bromovinylbenzene 
• 26456-05-3 10-methylacridinium perchlorate 
• 100-17-4 para-methoxynitrobenzene 
• 766-82-5 1-ethynyl-3-methyl-benzene 
• 13165-69-0 p-methoxy-N-sulfinylaniline 
• 4316-35-2 acetophenone dimethyl acetal 

Downstream Products

• 76757-58-9 (4-Methoxy-phenyl)-[2,2,2-trichloro-1-phenyl-eth-(E)-ylidene]-amine 
• 84905-14-6 N-p-methoxyphenyl-N-α-styrylbenzoylpyruvamide 
• 126522-56-3 4-methoxy-N-(1-phenylethyl)aniline 
• 860773-41-7 4-(2'-acetylphenyl)benzoic acid ethyl ester 
• 2743-01-3 (R)-N-(4-methoxyphenyl)-(1-phenylethyl)amine 
• 156092-13-6 (S)-4-methoxy-N-(1-phenylethyl)aniline 
• 1131891-07-0 1-(4-methoxyphenyl)-5-methyl-2-phenyl-1H-indole 
• 1131891-09-2 6-fluoro-1-(4-methoxyphenyl)-2-phenyl-1H-indole 
• 1131891-11-6 6-methoxy-1-(4-methoxyphenyl)-2-phenyl-1H-indole 
• 1131891-12-7 1-(4-methoxyphenyl)-2-phenyl-1H-benzo[g]indole 
• 52351-44-7 1-(4-methoxy-phenyl)-2-phenyl-1H-indole 
• 1189041-24-4 N-(1-(2-n-hexylphenyl)ethyl)-4-methoxyaniline 
• 1189041-25-5 N-(1-(2-n-decylphenyl)ethyl)-4-methoxyaniline 
• 1195390-29-4 4-methoxy-N-(2-phenyl-3-butyn-2-yl)aniline 

Relevant academic research and scientific papers

Gold(I) complexes bearing ring-fused benzoxazine-derived triazolylidenes and their use in C–N bond-forming processes

We report the synthesis and full characterization of a novel series of ring-fused benzoxazine-derived triazolium salts (1a–c) and their corresponding triazolylidene gold(I) complexes (2a–c). All new compounds were fully characterized by means of 1H and 13C NMR spectroscopy, elemental analyses, and mass spectroscopy and in the case of triazoliums 1a and 1b by single-crystal X-ray diffraction. The new triazolylidene gold complexes (2a–c) were tested as precatalysts in the hydroamination and hydrohydrazination of terminal alkynes employing aniline derivatives and hydrazine as nitrogen sources, respectively.

Syntheses of Triangular Gold Complexes and Their Applications in Hydroamination Reaction

Triangular all-metal complexes have aroused our research interest due to their unique structural and properties. Herein, through the facile reduction of μ3-oxo complex [μ3-O(PPh3Au)3]+BF4s

Synthesis and Catalytic Applications of Multinuclear Gold(I)-1,2,3-Triazolylidene Complexes

A series of mono- to trinuclear gold(I) complexes (1–3) supported by oxo-functionalized 1,2,3-triazolylidenes have been prepared. All new compounds were fully characterized by means of 1H and 13C NMR spectroscopy, elemental analyses, and in the case of complexes 1 and 2 by x-ray diffraction. The catalytic performance of the new triazolylidene gold complexes was tested in several hydroelementation and cyclization processes employing a variety of alkynes as starting materials. According to the overall results, the trinuclear complex 3 displayed the highest catalytic activity in all processes, providing good to excellent yields under mild reaction conditions.

Construction of Stable Metal–Organic Framework Platforms Embedding N-Heterocyclic Carbene Metal Complexes for Selective Catalysis

We report a bottom-up approach to immobilize catalysts into MOFs, including copper halides and gold chloride in a predictable manner. Interestingly, the structures of MOFs bearing NHC metal complexes maintained a similar 4-fold interpenetrated cube. They

Towards the rational design of ylide-substituted phosphines for gold(i)-catalysis: From inactive to ppm-level catalysis

The implementation of gold catalysis into large-scale processes suffers from the fact that most reactions still require high catalyst loadings to achieve efficient catalysis thus making upscaling impractical. Here, we report systematic studies on the impa

Chiral N-heterocyclic carbene-iridium complexes for asymmetric reduction of prochiral ketimines

Enantioselective reduction of imines to the corresponding chiral secondary amines has been studied using a series of chiral half-sandwich iridium complexes. Chiral N-heterocyclic carbene (NHC) ligands in these complexes were synthesized from readily available, naturally occurring amino acids. Inexpensive phenylsilane was used as a convenient hydrogen donor. Under the optimized conditions, Ir-NHC complexes could reduce ketimines in good yields, albeit with moderate enantiomeric excess (ee). The phenylglycine derived chiral NHC was shown to give the best Ir catalyst and it also gave the maximum ee compared to catalysts prepared from other NHCs in this series. The opposite enantiomer of the reduction product was always obtained while using the Ir complex bearing a valine based NHC. The yields were consistently high with a variety of imine substrates having different steric and electronic demands.

Regioselective mercury(I)/palladium(II)-catalyzed single-step approach for the synthesis of imines and 2-substituted indoles

An efficient synthesis of ketimines was achieved through a regioselective Hg(I)-catalyzed hydroamination of terminal acetylenes in the presence of anilines. The Pd(II)-catalyzed cycliza-tion of these imines into the 2-substituted indoles was satisfactorily carried out by a C-H acti-vation. In a single-step approach, a variety of 2-substituted indoles were also generated via a Hg(I)/Pd(II)-catalyzed, one-pot, two-step process, starting from anilines and terminal acetylenes. The arylacetylenes proved to be more effective than the alkyl derivatives.

Olefin Hydroarylation Catalyzed by a Single-Component Cobalt(-I) Complex

A single-component Co(-I) catalyst, [(PPh3)3Co(N2)]Li(THF)3, has been developed for olefin hydroarylations with (N-aryl)aryl imine substrates. More than 40 examples were examined under mild reaction conditions to afford the desired alkyl-arene product in good to excellent yields. Catalysis occurs in a regioselective manner to afford exclusively branched products with styrene-derived substrates or linear products for aliphatic olefins. Electron-withdrawing functional groups (e.g., -F, -CF3, and -CO2Me) were tolerated under the reaction conditions.

Pyridine Wingtip in [Pd(Py-tzNHC)2]2+ Complex Is a Proton Shuttle in the Catalytic Hydroamination of Alkynes

The cationic palladium(II) complex 1 of pyridyl-mesoionic carbene ligand catalyzes Markovnikov-selective intermolecular hydroamination between anilines and terminal alkynes into the corresponding imines. The reaction proceeds at room temperature, in the a

Oxidative Kinetic Resolution of Acyclic Amines Based on Equilibrium Control

An oxidative kinetic resolution of racemic acyclic amines was developed using an imine derivative as the resolving reagent and chiral phosphoric acid as the catalyst to give enantiomers in good yields with high to excellent enantioselectivities. The key t