13995-89-6

Upstream product

• 54893-95-7 ethyl 2-acetyl-3,3-bis(methylthio)acrylate 
• 51258-96-9 N-acetylbenzamidine 
• 1670-14-0 benzamidine monohydrochloride 

Downstream Products

• 1425383-91-0 ethyl 4-formyl-6-(methylthio)-2-phenylpyrimidine-5-carboxylate 
• 1425383-92-1 4-(methylthio)-2-phenylpyrimido[4,5-d]pyridazin-5(6H)-one 
• 1425379-71-0 4-(4-morpholinophenylamino)-2-phenylpyrimido[5,4-d]pyridazin-5(6H)-one 
• 1425387-25-2 C₁₃H₁₀N₄O₃S 

Relevant academic research and scientific papers

PYRIMIDO- PYRIDAZINONE COMPOUNDS AND USE THEREOF

The present application provides novel pyrimido-pyridazinone compounds and methods for preparing and using these compounds. These compounds are useful in treating inflammation in patients by administering one or more of the compounds to a patient. In one embodiment, the novel pyrimido-pyridazinone compound is of Formula (I) and R1 and R2 are defined herein.

Microwave-assisted solvent-free synthesis of highly functionalized pyrimidine derivatives

We here described an efficient method for the synthesis of a series of highly functionalized pyrimidines via the addition and condensation reaction of ketene dithioacetals with guanidine carbonate or amidine hydrochlorides by microwave irradiation under s