139962-70-2

Upstream product

• 536-78-7 3-ethylpyridine 
• 100-47-0 benzonitrile 
• 945607-79-4 [3-(2,2-dichloro-1-methylvinyl)-pyridin-2-yl]-carbamic acid tert-butyl ester 
• 98-80-6 phenylboronic acid 
• 149489-03-2 tert-butyl (3-ethylpyridin-2-yl)carbamate 
• 138343-75-6 tert-butyl (3-methylpyridin-2-yl)carbamate 
• 1603-40-3 3-methylpyridin-2-ylamine 
• 161987-58-2 1-(2-pivaloylaminopyridin-3-yl)ethanone 
• 86847-59-8 2-(pivaloylamino)pyridine 
• 945607-91-0 C₈H₈Cl₂N₂ 
• 945607-65-8 C₁₃H₁₆Cl₂N₂O 

Downstream Products

• 145934-33-4 3-Methyl-2-phenyl-7-phenacyl pyrrolo[2,3-b]pyridine 

Relevant academic research and scientific papers

2-SUBSTITUTED AZAIN DOLES AND 2 SUBSTITUTED THIENOPYRROLES, THEIR PRECURSORS AND NOVEL PROCESSES FOR THE PREPARATION THEREOF

The present invention relates generally to processes for the chemical synthesis of azaindole and thienopyrrole compounds, in particular azaindole and thienopyrrole compounds that are substituted at the 2-position of the azaindole or thienopyrrole ring, an

A general modular method of azaindole and thienopyrrole synthesis via Pd-catalyzed tandem couplings of gem-dichloroolefins

(Chemical Equation Presented) A palladium-catalyzed reaction of gem-dichloroolefins and a boronic acid via a tandem intramolecular C-N and intermolecular Suzuki coupling process gave corresponding substituted azaindoles or thienopyrroles. This method is a

A convenient method for the preparation of 5-, 6- and 7-azaindoles and their derivatives

The directed ortho lithiation of 2-tert-butoxycarbonylamino-3-methylpyridine (6a) has provided a convenient method for the preparation of 1H-pyrrolo[2,3-b]pyridine (4a, 7-azaindole). This procedure has been used to prepare a range of 3-substituted 2-tert-butoxycarbonylaminopyridines 6, 2- and 3-substituted and 2,3-disubstituted 1H-pyrrolo[2,3-b]pyridines 4 and shown to be of value in the preparation of 1H-pyrrolo[3,2-c]pyridine (15, 5-azaindole) and 1H-pyrrolo[2,3-c]pyridine (18, 6-azaindole) and derivatives.

ACTIVE COMPOUNDS

Therapeutically active compounds of the formula: wherein the variables are defined in the specification are provided

Reactions of β-(lithiomethyl)azines with nitriles as a route to pyrrolo-pyridines, - quinolines, -pyrazines, - quinoxalines and -pyrimidines

Deprotonation of 3-methylazines, followed by reaction with benzonitile, gives an intermediate which, on treatment with additional strong base, cyclises to give 2-phenyl[1H]-pyrrolo[2,3-b]pyridine. The application of this type of reaction to a variety of n