139962-77-9

Basic information

• Product Name: 4H-Pyrrolo[2,3-b]pyrazine, 6-(4-methoxyphenyl)-
• CAS NO: 139962-77-9
• Molecular Formula: C13H11N3O
• Molecular Weight: 225.25
• Mol File: 139962-77-9.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 4H-Pyrrolo[2,3-b]pyrazine, 6-(4-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-Pyrrolo[2,3-b]pyrazine, 6-(4-methoxyphenyl)-(139962-77-9)
• EPA Substance Registry System: 4H-Pyrrolo[2,3-b]pyrazine, 6-(4-methoxyphenyl)-(139962-77-9)

Safety Data

• Hazardous Substances Data: 139962-77-9(Hazardous Substances Data)

Upstream product

• 109-08-0 2-Methylpyrazine 
• 874-90-8 4-methoxybenzonitrile 
• 768-60-5 4-methoxyphenylacetylen 
• 724442-38-0 N-(3-chloropyrazin-2-yl)-methanesulfonamide 

Relevant articles and documents

An improved method for the synthesis of 6-substituted-5H-pyrrolo[2,3-b] pyrazines via palladium-catalyzed heteroannulation using microwave heating

We herein report an improved synthesis of 6-substituted-5H-pyrrolo[2,3-b] pyrazines utilizing microwave heating. The reaction is a palladium-catalyzed heteroannulation process followed by deprotection to yield the desired substrates in good yield.

Pyrrolopyrazines as kinase inhibitors

The invention relates to pyrrolo [2,3b]-pyrazine derivatives having the general formula (I) : ???wherein :R2 and R3 are identical or different and represent H, C1-C6 alkyl, said alkyl being a straight or branched-chain alkyl, which can be substituted,R6 i

Reactions of β-(lithiomethyl)azines with nitriles as a route to pyrrolo-pyridines, - quinolines, -pyrazines, - quinoxalines and -pyrimidines

Deprotonation of 3-methylazines, followed by reaction with benzonitile, gives an intermediate which, on treatment with additional strong base, cyclises to give 2-phenyl[1H]-pyrrolo[2,3-b]pyridine. The application of this type of reaction to a variety of n