139985-95-8

Usage

Chemical class

Carboxylic acids and derivatives

Chemical class

1,3-Piperidinedicarboxylic acid, 1-(1,1-dimethylethyl) 3-(phenylmethyl) ester belongs to the class of carboxylic acids and their derivatives, which are organic compounds containing a carboxyl functional group (-COOH).

Derivative of

Piperidine, a heterocyclic amine

Derivative of

It is derived from piperidine, which is a heterocyclic amine consisting of a six-membered ring containing one nitrogen atom.

Common use

Pharmaceutical industry as a building block for drug synthesis

Common use

The compound is widely used in the pharmaceutical industry, indicating its importance in the development and synthesis of various drugs.

Intermediate in

Production of pharmaceuticals

Intermediate in

It serves as an intermediate in the production of pharmaceuticals, meaning it is used in the synthesis process to form other compounds that are ultimately used in the final drug product.

Structure

Contains a piperidine ring, a tert-butyl group, and a phenylmethyl ester group

Structure

The compound's structure includes a piperidine ring, which is the core structure of the molecule. Additionally, it has a tert-butyl group (1,1-dimethylethyl) and a phenylmethyl ester group, which contribute to its chemical properties and reactivity.

Versatility

Suitable for various chemical reactions and synthetic applications

Versatility

Due to its unique structure, the compound is suitable for a wide range of chemical reactions and synthetic applications, making it a valuable building block in the pharmaceutical industry.

Upstream product

• 100-39-0 benzyl bromide 
• 71381-75-4 N-(tert-butyloxycarbonyl)nipecotic acid 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 139985-96-9 benzyl piperidine-3-carboxylate trifluoroacetate 
• 97231-90-8 piperidine-3-carboxylic acid benzyl ester 

Relevant academic research and scientific papers

NOVEL CYCLIC AMINOBENZOIC ACID DERIVATIVE

The present invention relates to cyclic amino benzoic acid derivatives which are effective in therapy of lipid metabolism abnormality, diabetes and the like as a human peroxisome proliferators-activated receptor (PPAR) agonist, in particular, as an agonist against human PPARα isoform, and addition salts thereof, and pharmaceutical compositions containing these compounds. A cyclic amino benzoic acid derivative represented by the general formula (1) [wherein a ring Ar represents an aryl group which may have substituent, or the like; Y represents a C1-C4 alkylene, C2-C4 alkenylene, C2-C4 alkynylene, or the like; Z represents an oxygen atom, sulfur atom or - (CH2)n- (n represents 0,1 or 2) ; X represents a hydrogen atom, halogen atom, lower alkyl group which may be substituted with a halogen atom, or the like; R represents a hydrogen atom or lower alkyl group, and -COOR substitutes for an ortho position or metha position of binding position of ring W] or a pharmaceutically acceptable salt thereof.

BETA-SECRETASE MODULATORS AND METHODS OF USE

The present invention comprises a new class of compounds useful for the modulation of Beta-secretase enzyme activity and for the treatment of Beta-secretase mediated diseases, including Alzheimer's disease (AD) and related conditions. In one embodiment, the compounds have a general Formula I wherein A, B, R3, R4, R5, i and j are defined herein. The invention also comprises pharmaceutical compositions including one or more compounds of Formula I, methods of use for these compounds, including treatment of AD and related diseases, by administering the compound(s) of Formula I, or compositions including them, to a subject. The invention also comprises further embodiments of Formulas II and III, intermediates and processes useful for the preparation of compounds of the invention.

Amido compounds and their use as pharmaceuticals

The present invention relates to inhibitors of 11-β hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of variou

Acetyl-CoA carboxylase inhibitors

Acetyl Coenzyme A Carboxylase inhibitors, pharmaceutical compositions containing such compounds and the use of such compounds to treat for example, Metabolic Syndrome including atherosclerosis, diabetes and obesity.