1399856-35-9Relevant academic research and scientific papers
Transition-metal-free stereoselective and regioselective hydroamination of 2-benzoylethynyl-4,5,6,7-tetrahydroindoles with amino acids
Sobenina, Lyubov N.,Tomilin, Denis N.,Ushakov, Igor A.,Mikhaleva, Albina I.,Trofimov, Boris A.
, p. 2084 - 2090 (2012)
A new family of unnatural amino acids possessing a tetrahydroindole moiety is obtained by nucleophilic addition of various amino acids to the triple bond of 2-benzoylethynyl-4,5,6,7-tetrahydroindoles. The reaction proceeds chemo-, regio- and stereospecifically in the presence of sodium hydroxide to give the Z-isomeric products in 35-72% yields. Georg Thieme Verlag Stuttgart ? New York.
