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Mycobactin is a group of small molecule siderophores produced by mycobacteria, especially Mycobacterium tuberculosis, to scavenge iron from the host environment. These compounds exhibit a high affinity for iron and the ability to chelate metal ions, playing a vital role in the survival, growth, and pathogenicity of mycobacteria due to the essential nature of iron as a nutrient.

1400-46-0

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1400-46-0 Usage

Uses

Used in Pharmaceutical Industry:
Mycobactin is used as a target for the development of new treatments for tuberculosis and other mycobacterial infections, given its crucial role in the survival and pathogenicity of the bacteria.
Used in Medical Research:
Mycobactin serves as a subject of study to understand the mechanisms of iron acquisition and utilization by pathogenic bacteria, which can provide insights into bacterial pathogenesis and potential therapeutic interventions.
Used in Diagnostics:
The presence and characteristics of mycobactin can be utilized in diagnostic assays to detect mycobacterial infections, particularly tuberculosis, by identifying the unique siderophores produced by these bacteria.
Used in Microbiology:
Mycobactin is used in microbiological research to study the iron-scavenging strategies of bacteria and their adaptation to host environments, contributing to the broader understanding of microbial pathogenesis and host-pathogen interactions.

Check Digit Verification of cas no

The CAS Registry Mumber 1400-46-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,4,0 and 0 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1400-46:
(6*1)+(5*4)+(4*0)+(3*0)+(2*4)+(1*6)=40
40 % 10 = 0
So 1400-46-0 is a valid CAS Registry Number.
InChI:InChI=1/C27H37N5O10/c33-17-31(39)13-6-1-2-10-20(29-24(36)21-16-42-25(30-21)18-8-3-4-11-22(18)34)27(38)41-15-12-23(35)28-19-9-5-7-14-32(40)26(19)37/h3-4,8,11,17,19-21,30,39-40H,1-2,5-7,9-10,12-16H2,(H,28,35)(H,29,36)/b25-18-

1400-46-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name [3-[(1-hydroxy-2-oxoazepan-3-yl)amino]-3-oxopropyl] 7-[formyl(hydroxy)amino]-2-[[(2Z)-2-(6-oxocyclohexa-2,4-dien-1-ylidene)-1,3-oxazolidine-4-carbonyl]amino]heptanoate

1.2 Other means of identification

Product number -
Other names Mycobactins

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1400-46-0 SDS

1400-46-0Upstream product

1400-46-0Downstream Products

1400-46-0Related news

Structure and absolute configuration of mycobactin (cas 1400-46-0) J09/03/2019

Mycobactin J 1 is a commercially available siderophore isolated from Mycobacterium avium subsp. paratuberculosis. There are discrepancies between previous reports of its structure and none have addressed its absolute configuration. We report here the complete structure and stereochemistry of myc...detailed

Mechanistic analysis of Mycobacterium tuberculosis Rv1347c, a lysine Nε-acyltransferase involved in mycobactin (cas 1400-46-0) biosynthesis☆09/02/2019

Mycobactin acylation plays a crucial role in the ability of Mycobacterium tuberculosis to acquire intracellular iron during infection. M. tuberculosis Rv1347c, the lysine Nε-acyltransferase responsible for mycobactin acylation, represents a valid target for the development of novel anti-tubercu...detailed

The investigation of the truncated mbtA gene within the mycobactin (cas 1400-46-0) cluster of Mycobacterium avium subspecies paratuberculosis as a novel diagnostic marker for real-time PCR09/01/2019

The inability of Mycobacterium avium subspecies paratuberculosis (MAP) to produce endogenous mycobactin in-vitro is most likely due to the presence of a truncated mbtA gene within the mycobactin cluster of MAP. The main goal of this study was to investigate this unique mbtA truncation as a poten...detailed

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