1400634-70-9

Upstream product

• 19652-13-2 5-amino-3-(4-methoxylphenyl)-1-phenyl-1H-pyrazole 
• 1400634-72-1 C₁₇H₁₅N₃O₂ 
• 77287-34-4 formamide 

Relevant academic research and scientific papers

One-flask synthesis of pyrazolo[3,4-d]pyrimidines from 5-aminopyrazoles and mechanistic study

A novel one-flask synthetic method was developed in which 5-aminopyrazoles were reacted with N,N-substituted amides in the presence of PBr3. Hexamethyldisilazane was then added to perform heterocyclization to produce the corresponding pyrazolo[

Selective synthesis of pyrazolo[3,4-d]pyrimidine, N-(1H-pyrazol-5-yl) formamide, or N-(1H-pyrazol-5-yl)formamidine derivatives from N-1-substituted-5-aminopyrazoles with new Vilsmeier-type reagents

Various halomethyleniminium salts as novel Vilsmeier agents were synthesized from formamide or N-methylformamide with POCl3. Treatment of N-1-substituted-aminopyrazoles including N-1-phenyl-5-aminopyrazoles, N-1-(2-pyridinyl)-5-aminopyrazoles,

Evaluation of electrophilic heteroaromatic substitution: Synthesis of heteroaromatic-fused pyrimidine derivatives via sequential three-component heterocyclization

A new sequential three-component heterocyclization was developed by reacting aromatic and heterocyclic substrates, including aminobenzenes, 1-aminonaphthalene, 2-aminopyrazines, 5-aminopyrazoles, 3-aminopyridine, 5-aminopyrimidine, 5-aminoquinoline, and 8

One-pot synthesis and antiproliferative evaluation of pyrazolo[3,4-d] pyrimidine derivatives

An efficient one-pot methodology for the synthesis of pyrazolo[3,4-d] pyrimidines was developed by using 5-aminopyrazoles with formamide in presence of PBr3 as the coupling agent. Among the examples presented in this work, compounds 41 and 54-5