19652-13-2

Usage

Uses

Used in Pharmaceutical Industry:
5-Amino-3-(4-methoxyphenyl)-1-phenylpyrazole is used as a key intermediate compound for the synthesis of pyrazolo[3,4-b]pyridines derivatives. These derivatives have demonstrated potent anti-inflammatory activity, particularly against interleukin-6 (IL-6), making them valuable in the development of new anti-inflammatory drugs.
Used in Agrochemical Industry:
In the agrochemical industry, 5-Amino-3-(4-methoxyphenyl)-1-phenylpyrazole and its derivatives may be utilized for the development of novel compounds with potential applications in pest control, crop protection, and other related areas. The specific application reasons and types may vary based on the derivative's properties and the target pest or crop.

InChI:InChI=1/C16H15N3O/c1-20-14-9-7-12(8-10-14)15-11-16(17)19(18-15)13-5-3-2-4-6-13/h2-11H,17H2,1H3

Upstream product

• 532-11-6 anethole trithione 
• 100-63-0 phenylhydrazine 
• 121-98-2 methyl 4-methoxybenzoate 
• 831-30-1 5-(p-methoxyphenyl)dithia<1,2>cyclopenten-3-one 
• 3672-47-7 3-oxo-3-(4'-methoxyphenyl)propanenitrile 

Downstream Products

• 90012-53-6 N-ethoxycarbonyl-N'-<3-(p-anisyl)-1-phenylpyrazol-5-yl>thiourea 
• 1061705-07-4 C₂₇H₂₁N₃O₃ 
• 1061705-10-9 C₂₂H₁₉N₃O₂ 
• 1061704-91-3 C₂₂H₂₁N₃O₂ 
• 1061704-78-6 C₂₇H₃₁N₃O₅ 
• 1257533-44-0 N′-[4-formyl-3-(4-methoxylphenyl)-1-phenyl-1H-pyrazol-5-yl]-N,N-dimethylmethanimidamide 
• 1312014-68-8 3,5-dihydro-9-methoxy-1-(4-methoxyphenyl)-3,5-diphenyl-2,3,4,5,6-pentaazadibenzo[4,5:6,7]cyclohepta[1,2,3-cd]s-indacene 
• 1312014-65-5 4-(2-chlorophenyl)-3,5-bis(4-methoxyphenyl)-1,7-diphenyl-1,7-dihydrodipyrazolo[3,4-b:4',3'-e]pyridine 
• 1400634-70-9 3-(4-methoxylphenyl)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine 
• 1419612-33-1 N'-(1-phenyl-3-(4-methoxylphenyl)-1H-pyrazol-5-yl)-N-methylmethanimidamide 
• 1439359-36-0 C₃₀H₂₅N₃O₄ 

Relevant academic research and scientific papers

Synthesis of novel twisted heterocyclic analogues of s-indacenes

A series of novel compounds as candidates for OLED applications were synthesized by cyclization reactions of neighbouring rings in dipyrazolo[3,4-b:4',3'-e]pyridines 8-12. The desymmetrization of these molecules leading to 14 can be performed using both KOH/isoquinoline or palladium catalysts. The resulting structures contain a helical arrangement of four different rings. ARKAT-USA, Inc.

Synthesis of some novel fluorinated pyrazolo[3,4-b]pyridines

Reaction of 5-amino-3-substituted pyrazoles (1a-c) and 5-amino-1,3- disubstituted pyrazoles (1d-i) with fluorinated-β-diketones (2) results in the formation of the single isomer of pyrazolo[3,4-b]pyridines (4a-h). A one-pot procedure for the synthesis of