1401031-28-4

Usage

Molecular structure

2-[(9R)-9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl]acetaldehyde has a complex molecular structure that includes a spiro decane ring fused with a pyridine ring and an aldehyde functional group.

Spiro compound

The presence of a spiro decane ring in the structure indicates that 2-[(9R)-9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl]acetaldehyde belongs to the class of spiro compounds, which have been found to exhibit various biological activities.

Aldehyde functional group

The aldehyde group in the molecule suggests that it can undergo a range of chemical reactions, making it a versatile building block for the synthesis of more complex molecules.

Potential pharmaceutical applications

Due to its unique structure and the presence of biologically active components, 2-[(9R)-9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl]acetaldehyde has potential applications in the pharmaceutical industry.

Upstream product

• 855398-58-2 (+/-)-6-oxaspiro[4.5]decan-9-ol 
• 120-92-3 cyclopentanone 
• 1401031-37-5 2-[9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl]acetonitrile 
• 855398-57-1 6-oxa-spiro[4.5]decan-9-one 
• 1401031-38-6 2-[(9R)-9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl]acetonitrile 

Downstream Products

• 1401028-24-7 TRV-130 

Relevant academic research and scientific papers

METHOD FOR PREPARING OXASPIROCYCLE DERIVATIVE, AND INTERMEDIATE THEREOF

A method for preparing an oxaspirocycle derivative and an intermediate thereof are described. The method reduces reaction steps, improves reaction yield, is simple and easy to operate, and is favorable for industrial large-scale production.

Opioid receptor agonists and application thereof

The invention discloses compounds and salts thereof that can be used as opioid receptor ligands, a preparation method of the compounds, compositions containing the compounds, and a use of the compounds as [mu] opioid receptor agonists; the compounds are used for treatment of [mu] opioid receptor-mediated related diseases, such as pains and pain-related disorders.

DEUTERATED COMPOUNDS FOR TREATING PAIN

The invention provides novel chemical compounds useful for treating pain or a related disease or disorder thereof, and pharmaceutical composition and methods of preparation and use thereof.

COMBINATIONS OF OPIOID RECEPTOR LIGANDS AND CYTOCHROME P450 INHIBITORS

This application described compounds that can act as opioid receptor ligands, and compositions comprising the compounds and cytochrome P450 inhibitors, which can be used in the treatment of, for example, pain and pain related disorders.

OPIOID RECEPTOR LIGANDS AND METHODS OF USING AND MAKING SAME

This application describes compounds that can act as opioid receptor ligands, which compounds can be used in the treatment of, for example, pain and pain related disorders.