1401111-20-3Relevant academic research and scientific papers
Synthesis of Sultones from Chlorosulfates by a Complex Cascade Reaction Occurring under Mild Thermal Conditions
Cala, Lara,Rivilla, Iván,Cossío, Fernando P.,Fa?anás, Francisco J.,Rodríguez, Félix
, p. 13083 - 13087 (2019)
Chlorosulfate derivatives are interesting reagents that have been traditionally used to get other sulfur-containing compounds by formal nucleophilic substitution of the chlorine atom. This work describes a different mode of reactivity of alkyne-containing
Lewis acid catalyzed cascade annulation of alkynols with α-ketoesters: A facile access to γ-spiroketal-γ-lactones
Kambale, Digambar A.,Thorat, Sagar S.,Pratapure, Madhukar S.,Gonnade, Rajesh G.,Kontham, Ravindar
supporting information, p. 6641 - 6644 (2017/07/10)
A novel Lewis acid catalyzed intermolecular cascade annulation of alkynols with α-ketoesters has been developed. This simple and efficient cascade annulation proceeds through a 5-exo-dig cyclization of alkynols followed by annulation with α-ketoester to provide a wide variety of unsaturated γ-spiroketal-γ-lactones (1,6-dioxaspiro[4.4]non-3-en-2-ones) related to many natural products.
