1401216-79-2

Upstream product

• 7649-92-5 2-(4-fluorobenzoyl)benzoic acid 
• 1401216-75-8 2-(3,5-dinitro-4-fluorobenzoyl)benzoic acid 
• 108-46-3 recorcinol 
• 462-06-6 fluorobenzene 

Downstream Products

• 1401216-91-8 3-(3,5-dibromo-2,4-dihydroxyphenyl)-3-(3,5-dinitro-4-fluorophenyl)phthalide 
• 108-46-3 recorcinol 
• 1401216-89-4 3-(2,4-diacetoxyphenyl)-3-(3,5-dinitro-4-fluorophenyl)phthalide 

Relevant academic research and scientific papers

Studies on synthetic and structural characterization of new fluorine substituted phthalides of pharmaceutical interest

An efficient and economical synthesis of some new fluorine substituted phthalides was accomplished from two γ-keto acids, 2-(4-fluorobenzoyl) benzoic acid and 2-(3,5-dinitro-4-flurobenzoyl)benzoic acid. Each acid was reacted with various phenolic compounds in presence of catalytic quantity of concentrated sulphuric acid to get the phthalides. The structures of the synthesized compounds were established on the basis of their elemental analysis, spectral data and chemical reactions. Some of the synthesized phthalides exhibited antibacterial and antifungal activity on antimicrobial screening against human pathogenic bacteria and fungi.