1401247-16-2Relevant academic research and scientific papers
KOH-catalyzed regioselective ring openings of N-tosylaziridines with malonates in acetone
Li, Xing,Su, Jijuan,Chang, Honghong,Li, Gong,Li, Yanwei,Wei, Wenlong
, p. 446 - 450,5 (2020/07/30)
A simple and efficient method has been developed which describes KOH-oriented catalytic regioselective ring-opening reactions of various N-tosylaziridines with malonates. In the presence of 20 mol% KOH, most N-tosylaziridines can smoothly react with malonates to give the corresponding products in good to excellent yields (up to 99%) and with good to excellent regioselectivity under mild experimental conditions.
